如何计算Selection Coefficient
learn.whatIsHeading
The selection coefficient (s) quantifies the fitness disadvantage of a genotype. If the fittest genotype has relative fitness 1, a genotype with fitness (1−s) has selection coefficient s.
分步指南
- 1s = 1 − w_aa/w_AA
- 2Allele frequency change: Δq ≈ −sq²p/(1−sq²)
例题解析
输入
w_AA=1.0 · w_aa=0.7
结果
s = 0.3 (30% fitness reduction)
Moderate selection against recessive
准备好计算了吗？尝试免费的 Selection Coefficient 计算器
自己尝试一下 →