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How to Calculate Corrected Calcium

What is Corrected Calcium?

Corrected calcium adjusts serum calcium for albumin levels, better reflecting true ionized calcium status and clinical significance.

Formula

Calculate: Corrected Ca = Measured Ca + 0.8 × (4.0 - Albumin)
Ca
Measured Ca + 0 — Measured Ca + 0

Step-by-Step Guide

  1. 1Calculate: Corrected Ca = Measured Ca + 0.8 × (4.0 - Albumin)
  2. 2Or use ionized calcium directly if available
  3. 3Normal corrected calcium 8.5-10.2 mg/dL

Worked Examples

Input
Total Ca 7.8 mg/dL, albumin 2.5 g/dL
Result
Corrected Ca = 7.8 + 0.8(4.0-2.5) = 9 mg/dL (normal)
Not hypocalcemic

Common Mistakes to Avoid

  • Forgetting albumin correction in hypoalbuminemic patients
  • Treating low total calcium as pathologic without correction

Frequently Asked Questions

Why adjust for albumin?

Albumin binds ~45% of serum calcium; low albumin falsely lowers total calcium without affecting ionized calcium.

When is correction unnecessary?

If ionized calcium is directly measured, no correction needed; it's the physiologically active form.

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